Allgemeine zellbasierte Assays
Allgemeine zellbasierte Assays
Thermo Scientific™ Tango™ HRH3-bla U2OS DA Assay Kit
The Tango™ HRH3-bla U2OS DA (Division Arrested) cells contain the human Histamine Receptor H3 (HRH3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ AGTRL1-bla U2OS Cells
The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ Kinase Tracer 236, 50 μM
Im LanthaScreen™ Eu-Kinase-Bindungsassay wird die Bindung eines Alexa Fluor™ Konjugats oder einer Markierungssubstanz wie der Kinase Markierungssubstanz 236 an eine Kinase durch Zugabe eines mit Eu markierten Anti-Tag-Antikörpers nachgewiesen.
Thermo Scientific™ CellSensor™ TrkA-NFAT-bla CHO-K1-Zelllinie
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
Thermo Scientific™ CellSensor™ CRE-bla HEK293T-Zelllinie
The CellSensor™ CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE).
Thermo Scientific™ GeneBLAzer™ ADRB2-CRE-bla CHO-K1 Cells
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ CXCR4-bla U2OS-Zellen
The Tango™ CXCR4-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 4 (CXCR4) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ ADORA3-Gα15-NFAT-bla CHO-K1 cells
GeneBLAzer™ ADORA3-Ga15-NFAT-bla CHO-K1 cells contain the human Adenosine A3 Receptor (ADORA3) stably integrated into the GeneBLAzer™ Ga15-NFAT-bla CHO-K1 cell line.
Thermo Scientific™ CellSensor™ NFAT-bla Jurkat-Zelllinie
The CellSensor™ NFAT-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into Jurkat cells.
Thermo Scientific™ CellSensor™ NFAT CHO-K1 DA Assay-Kit
The CellSensor™ NFAT CHO-K1 DA (Division Arrested) cells contain a beta-lactamase (bla) reporter gene under control of a Nuclear Factor of Activated T Cells (NFAT) response element stably integrated into CHO-K1 cells.
Thermo Scientific™ Tango™ OPRL1-bla U2OS Cells
The Tango™ OPRL1-bla U2OS cells contain the human Opioid Receptor-Like 1 (OPRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ PPARγ-UAS-bla HEK 293H Cells
PPAR gamma-UAS-bla HEK 293H cells contain the ligand-binding domain (LBD) of the human Peroxisome Proliferator-Activated Receptor-gamma (PPAR gamma) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293H cell line.
Thermo Scientific™ GeneBLAzer™ ERR Alpha DA Assay Kit
Bei GeneBLAzer™ERR-alpha DA (Division Arrested)-Zellen und ERR-alpha-UAS-bla HEK 293T-Zellen ist die Ligandenbindungsdomäne (LBD) des humanen Estrogen-Related-Rezeptors alpha (ERR-alpha), fusioniert mit der DNA-Bindungsdomäne von GAL4, stabil in die GeneBLAzer™UAS-bla HEK 293T-Zelllinie integriert.
Thermo Scientific™ Tango™ DRD1-bla U2OS Cells
The Tango™ DRD1-bla U2OS cells contain the human Dopamine Receptor 1 (DRD1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.