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VANGL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 21492-1-AP-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16841085

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

Van Gogh is an alternate name for the Drosophila strabismus protein. Van Gogh like-2 (VANGL2) is a 521 amino acidprotein in vertebrates similar to strabismus 1 of Drosophila and a component of the frizzled-disheveled tissue polarity pathway. It interacts through it′s C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3 and is a potent tumor suppressor. It ispredomitly involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a crucial role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. VANGL2 is required for polarization and movement of myocardializing cells and seems to act via RHOA signaling to regulate this process. It is expressed in a wide range of tissues.
Spezifikation

Spezifikation

VANGL2
Polyclonal
Unconjugated
VANGL2
KIAA1215, Loop tail protein 1 homolog, LPP1, LTAP, STB1, STBM, STBM1, Strabismus 1, Van Gogh like protein 2, Vang like protein 2, VANGL2
Rabbit
Antigen Affinity Chromatography
RUO
289229, 57216, 93840
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P84889, Q91ZD4, Q9ULK5
Vangl2
VANGL2 Fusion Protein Ag15833
150 μL
Primary
Human, Mouse, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote