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TRAF7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 11780-1-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16839083

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

TRAFs are signal transducers for members of TNFR superfamily. These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis. TRAF7, a novel 670 A. A protein, is a human homolog of mouse Traf7 andconsists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus. It has E3-ubiquitin ligase activity for self-ubiquitination. TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways. It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.
Spezifikation

Spezifikation

TRAF7
Polyclonal
Unconjugated
TRAF7
RFWD1, RING finger protein 119, RNF119, TRAF7
Rabbit
Antigen Affinity Chromatography
RUO
224619, 360491, 84231
Antibody
IgG
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.17 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q6Q0C0, Q922B6
Traf7
TRAF7 Fusion Protein Ag2414
20 μL
Primary
Human, Rat, Mouse
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote