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TRAF7 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 11780-1-AP-20UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
TRAFs are signal transducers for members of TNFR superfamily. These are critically involved in activation of MAP3K family members involved in NF-kappaB and JNK activation and apoptosis. TRAF7, a novel 670 A. A protein, is a human homolog of mouse Traf7 andconsists of an N-terminal RING finger domain, central TRAF domain, a coiled-coil motif and 7 WD40 repeats at the C-terminus. It has E3-ubiquitin ligase activity for self-ubiquitination. TRAF7 specifically interacts with MEKK3 and mediates MEKK3-induced AP1 and CHOP activation and induces apoptosis through Caspase-independent pathways. It is a multifunctional protein involved in sumoylation and negative regulation of c-Myb, thereby regulating proliferation and differentiation of hematopoietic cells.Spezifikation
TRAF7 | |
Polyclonal | |
Unconjugated | |
TRAF7 | |
RFWD1, RING finger protein 119, RNF119, TRAF7 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
224619, 360491, 84231 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
0.17 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q6Q0C0, Q922B6 | |
Traf7 | |
TRAF7 Fusion Protein Ag2414 | |
20 μL | |
Primary | |
Human, Rat, Mouse | |
Antibody | |
IgG |