missing translation for 'onlineSavingsMsg'
Learn More
Learn More
SSEA-1 Mouse, PE, Clone: MC480, BD
Mouse Monoclonal Antibody
250.00 CHF - 575.00 CHF
Spezifikation
| Antigen | SSEA-1 |
|---|---|
| Klon | MC480 |
| Anwendungen | Flow Cytometry |
| Klassifikation | Monoclonal |
| Konjugat | PE |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15830569
|
BD Biosciences
560886 |
25 Tests |
250.00 CHF
1 Stück |
Verfügbar ab: 16-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
|
15819968
|
BD Biosciences
560142 |
100 Tests |
575.00 CHF
1 Stück |
Verfügbar ab: 23-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
Beschreibung
The MC480 monoclonal antibody reacts with Stage-Specific Embryonic A ntigen-1 (SSEA-1), which is a terminal carbohydrate epitope (3-fucosyl-N-acetyllactosamine or 3-FAL) on glycoproteins and lactose series glycolipids. SSEA-1 is related to Lewis blood group antigens and is found in a variety of embryonic and adult tissues and cancers. As its name implies, the expression of SSEA-1 is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. However, its expression pattern differs in the human and mouse. In the human, SSEA-1 is not found on embryonic stem (ES) cells, embryonic inner cell mass (ICM), or teratocarcinoma (embryonal carcinoma or EC) cells. As human EC and ES cells undergo differentiation, SSEA-1 expression is upregulated. In the adult, the same epitope is expressed as CD15 on granulocytes and monocytes, but not lymphocytes or dendritic cells. In the mouse, SSEA-1 is found on EC, ES, and primordial germ cells, 8-cell to blastocyst embryos, ICM, and on subpopulations of cells in the adult central nervous system, including stem cells. In contrast to the human, SSEA-1 expression is reduced as mouse EC and ES cells undergo differentiation.
Spezifikation
| SSEA-1 | |
| Flow Cytometry | |
| PE | |
| RUO | |
| Aqueous buffered solution containing BSA, protein stabilizer, and ≤0.09% sodium azide. | |
| IgM κ | |
| Affinity Purified | |
| 3-FAL, X-hapten, LeX antigen, CD15 |
| MC480 | |
| Monoclonal | |
| Mouse | |
| Human, Mouse | |
| Mouse Teratocarcinoma Cell Line | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.