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SPP Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 20416-1-AP-20UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection. May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1. Cleaves the integral membrane protein XBP1 isoform 1 in a DERL1/RNF139- dependent manner.Spezifikation
| SPP | |
| Polyclonal | |
| Unconjugated | |
| HM13 | |
| H13, hIMP1, histocompatibility (minor) 13, HM13, IMP 1, IMP1, IMPAS, IMPAS 1, Intramembrane protease 1, MSTP086, Presenilin like protein 3, PSENL3, PSL3, Signal peptide peptidase, SPP | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 14950, 81502 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.13 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q8TCT9, Q9D8V0 | |
| Hm13 | |
| SPP Fusion Protein Ag14158 | |
| 20 μL | |
| Primary | |
| Mouse, Human | |
| Antibody | |
| IgG |