missing translation for 'onlineSavingsMsg'
Learn More

PSME2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 12937-2-AP-150UL

Additional Details : Gewicht : 0.00010kg

 Lernen Sie weitere Varianten dieses

Artikelnummer. 16840904

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 28-06-2022
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

Proteolytic degradation is critical to the maintece of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cell cytosol and nucleus. Others are degraded via the vacuolar pathway which includes endosomes, lysosomes, and the endoplasmic reticulum. The 26S proteasome is an ATP-dependent, multisubunit (approximately 31), barrel-shaped molecular machine with an apparent molecular weight of approximately 2.5 MDa. It consists of a 20S proteolytic core complex which is crowned at one or both ends by 19S regulatory subunit complexes. The 19S regulatory subunits recognize ubiquitinated proteins and play an essential role in unfolding and translocating targets into the lumen of the 20S subunit. An enzymatic cascade is responsible for the attachment of multiple ubiquitin molecules to lysine residues of proteins targeted for degradation. Several genetic diseases are associated with defects in the ubiquitin-proteasome pathway. Some examples of affected proteins include those linked to cystic fibrosis, Angelman′s syndrome, and Liddle syndrome.
Spezifikation

Spezifikation

PSME2
Polyclonal
Unconjugated
PSME2
PA28B, PA28beta, PSME2, REG beta, REGbeta
Rabbit
Antigen Affinity Chromatography
RUO
19188, 29614, 5721
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P97372, Q63798, Q9UL46
Psme2
PSME2 Fusion Protein Ag3986
150 μL
Primary
Human, Mouse, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote