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PEX5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 12545-1-AP-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16840304

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 01-07-2022
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Beschreibung

Beschreibung

This antibody recognizes endogenous PEX5, which migrates with an apparent molecular mass of 80 kDa.

The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.
Spezifikation

Spezifikation

PEX5
Polyclonal
Unconjugated
PEX5
Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1
Rabbit
Antigen Affinity Chromatography
RUO
19305, 312703, 5830
Antibody
IgG
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
0.19 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O09012, P50542, Q2M2R8
Pex5
PEX5 Fusion Protein Ag3268
150 μL
Primary
Human, Mouse, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote