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ACROBiosystems Human Jagged 1 / JAG1 Protein, His Tag

Marke:  ACROBiosystems JA1-H52H9-1MG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15827167

  • 2533.22 CHF / 1 Milligramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 112.3 kDa. The protein migrates as 130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_000205.1
HEK293
Human
112.3 kDa
1 mg
Gln 34 - Ser 1046
CD339,JAG1,Jagged1,hJ1,JAGL1
Unconjugated
PBS, pH7.4
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>90% as determined by SDS-PAGE
Human Jagged 1, His Tag (JA1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 34 - Ser 1046 (Accession # P78504-1).
-20°C
Jagged 1
His Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation