missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Human IL-1 beta, Recombinant Protein
E. coli Recombinant Protein
79.75 CHF - 346.00 CHF
Spezifikation
Zur Verwendung mit (Anwendung) | Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot |
---|---|
Lagerungsbedingungen | -20°C |
Kennzeichnung | RUO |
Spezifische Reaktivität | Human |
Konjugat | Unconjugated |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
---|---|---|---|---|---|---|---|---|---|
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
17164183
|
Invitrogen™
A42509 |
50 μg |
346.00 CHF
50 Mikrogramm |
Verfügbar ab: 29-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
|||||
17154183
|
Invitrogen™
A42508 |
5 μg |
79.75 CHF
5 Mikrogramm |
Lager vorrätigLoggen Sie sich ein, um den Lagerbestand zu sehen
|
|||||
17174193
|
Invitrogen™
A42521 |
5 x 5 μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
||||||
17144183
|
Invitrogen™
A42507 |
5 x 5 μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
||||||
Beschreibung
Interleukin-1 beta (IL-1 beta) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 beta is synthesized in response to inflammatory stimuli as a 31 kDa inactive pro-form that accumulates in the cytosol. Cleavage of pro-IL-1 beta into the active 17 kDa protein requires the activation of inflammasomes, which are multi-protein complexes that respond to pathogens, stress conditions, and other danger signals. Inflammasome activation triggers the processing of the caspase-1 precursor into its active form, which in turn cleaves pro-IL-1 beta. IL-1 beta lacks a signal sequence peptide for classical ER/Golgi pathway and is secreted alongside caspase-1 via an alternate and incompletely understood mechanism. Although IL-1 beta is most often secreted in its active form, secretion of the uncleaved protein may be detectable under some biological conditions. IL-1 beta signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 alpha. IL-1 beta activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 beta play an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses to infection and injury. Elevated levels of IL-1 beta have been associated with many chronic inflammatory conditions IL-1 beta neutralizing antibodies potential therapeutic value.Spezifikation
Control, ELISA, Functional Assay, Immunohistochemistry, Western Blot | |
RUO | |
Unconjugated | |
Lyophilized |
-20°C | |
Human | |
Recombinant | |
≥ 90% |