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GAS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 11941-2-AP-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16839343

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney.
Spezifikation

Spezifikation

GAS2
Polyclonal
Unconjugated
GAS2
GAS 2, GAS2, growth arrest 2
Rabbit
Antigen Affinity Chromatography
RUO
14453, 2620, 499156
Antibody
IgG
Western Blot, Immunohistochemistry (Paraffin)
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43903, P11862
Gas2
GAS2 Fusion Protein Ag2540
20 μL
Primary
Rat, Mouse, Human
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote