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GAS2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

133.80 CHF - 381.34 CHF

Spezifikation

Antigen GAS2
Konzentration 0.33 mg/mL
Anwendungen Western Blot, Immunohistochemistry (Paraffin)
Klassifikation Polyclonal
Konjugat Unconjugated
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
16839343
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Proteintech
11941-2-AP-20UL
20 μL
133.80 CHF
20 Mikroliter
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Verfügbar ab: 17-04-2024
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16829343
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Proteintech
11941-2-AP-150UL
150 μL
381.34 CHF
150 Mikroliter
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Sparen Sie bis zu 
»
Verfügbar ab: 17-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

Gas2 is a 313 amino acid protein encoded by the human gene GAS2. Gas2 is thought to play a role in apoptosis by acting as a cell death substrate for caspases. Gas2, a component of the microfilament system, is cleaved by a caspase (caspase-3 and caspase-7) at Asparagine 278 during apoptosis. The cleaved form resulting from this dramatically induces the rearrangement of the Actin cytoskeleton and causes potent changes in the shape of the affected cells. Gas2 is believed to also be involved in the membrane ruffling process. During the G0-G1 transition phase Gas2 can be found phosphorylated on its serine residues. Gas2 is a cytoskeleton and peripheral membrane protein that co-localizes with Actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Gas2 is mainly membrane-associated but when hyperphosphorylated it will accumulate at membrane ruffles. Gas2 is specifically expressed at growth arrest and is ubiquitously expressed with highest levels found in liver, lung and kidney.
Spezifikation

Spezifikation

GAS2
Western Blot, Immunohistochemistry (Paraffin)
Unconjugated
Rabbit
Rat, Mouse, Human
O43903, P11862
14453, 2620, 499156
GAS2 Fusion Protein Ag2540
Primary
-20°C
GAS2
0.33 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
GAS 2, GAS2, growth arrest 2
Gas2
IgG
Antigen Affinity Chromatography
Antibody
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Sicherheitsdatenblatt (SDS)
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Dokumentation

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