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  8. (-)-Epicatechin gallate, Thermo Scientific Chemicals

(-)-Epicatechin gallate, Thermo Scientific Chemicals

Codice prodotto. 15473519
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Codice prodotto. 15473519 Fornitore Thermo Scientific Alfa Aesar N. del fornitore J60814.MA
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Descrizione

A natural product from green tea that induces apoptosis

(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.

Solubility
Soluble in water, acetone, DMSO, methanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 1257-08-5
Formula molecolare C22H18O10
Molecular Weight (g/mol) 442.376
Numero MDL MFCD00075936
InChI Key LSHVYAFMTMFKBA-TZIWHRDSSA-N
Sinonimo =--epicatechin gallate, epicatechin gallate, =--epicatechin-3-o-gallate, l-epicatechin gallate, =--epicatechin-3-gallate, =--epicatechingallate, epicatechin monogallate, --epicatechin 3-o-gallate, teatannin, epicatechol, gallate
PubChem CID 107905
ChEBI CHEBI:70255
IUPAC Name [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
SMILES C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O

Specifica

Materiale o nome chimico (-)-Epicatechin gallate
Colore White
Quantità 10 mg
Informazioni di solubilità Soluble in water,acetone,DMSO,methanol.
Peso formulazione 442.37
Forma fisica Powder

RUO – Research Use Only

Titolo del prodotto
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