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Invitrogen™ DYRK2 Recombinant Human Protein
DYRK2 is also known as dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2. Recombinant full-length human DYRK2 was expressed in E. coli cells using an N-terminal GST tag.
Marke: Invitrogen™ PV6333
Additional Details : Gewicht : 0.01000kg
Beschreibung
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development and is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 expressed in E. coli demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. DYRK2 also regulates p53 to induce apoptosis in response to DNA damage.
- Validated in LanthaScreen™ Kinase Binding Assay
- Protocols available for simple use and optimized performance
- Multiple pack sizes available for convenient use
Spezifikation
| Enzyme and Protein Activity Assay, Industrial and Applied Science, Kinase Assay, Kinase Biology, Kinase Proteins and Expression Reagents, Pharma and Biopharma, Protein Assays and Analysis, Protein Biology, Target and Lead Identification and Validation | |
| 92.9kDa | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. | |
| Human | |
| GST Tag |
| 50mM Tris-HCl pH 7.5, 150mM NaCl, 0.25mM DTT, 10mM glutathione, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol | |
| 1mg | |
| FLJ21217, FLJ21365 | |
| Recombinant |