missing translation for 'onlineSavingsMsg'
Learn More

CD274 Mouse anti-Human, PE, Clone: MIH1, BD

Mouse Monoclonal Antibody

Marke:  BD Biosciences 557924

Additional Details : Gewicht : 0.02000kg

 Lernen Sie weitere Varianten dieses

Artikelnummer. 15819118

  • 388.00 CHF / 1 Stück


Verfügbar ab
29-06-2021
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells, including IFN- γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2 on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts, myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.

Spezifikation

Spezifikation

CD274
MIH1
B7-H1, PD-L1
Affinity Purified
IgG1, κ
RUO
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
PE
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
100 Tests
Immunology
Primary
Human
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

For Research Use Only.