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CD274 Mouse anti-Human, PE, Clone: MIH1, BD
Mouse Monoclonal Antibody
241.00 CHF - 499.00 CHF
Spezifikation
Antigen | CD274 |
---|---|
Klon | MIH1 |
Anwendungen | Flow Cytometry |
Klassifikation | Monoclonal |
Konjugat | PE |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
15821339
|
BD Biosciences
561787 |
25 Tests |
241.00 CHF
1 Stück |
Verfügbar ab: 15-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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15819118
|
BD Biosciences
557924 |
100 Tests |
499.00 CHF
1 Stück |
Verfügbar ab: 06-05-2024
Loggen Sie sich ein, um den Lagerbestand zu sehen |
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Beschreibung
PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells, including IFN- γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2 on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts, myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2 and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.
Spezifikation
CD274 | |
Flow Cytometry | |
PE | |
RUO | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
MIH1 | |
Monoclonal | |
Mouse | |
Human | |
IgG1 κ | |
Affinity Purified | |
B7-H1, PD-L1 |
For Research Use Only.