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Invitrogen™ Carbonic Anhydrase IX Recombinant Rabbit Monoclonal Antibody (005), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Marca: Invitrogen™ MA552134
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Descrizione
Carbonic anhydrase (CA) is an enzyme that assists rapid interconversion of carbon dioxide and water into carbonic acid, protons, and bicarbonate ions. It is abundant in all mammalian tissues. There are many genes that are inducible by hypoxia, via HIF-1 alpha. CA IX is one of the most inducible genes because of its stability and location within the membrane. Carbonic anhydrases have a widespread role in regulating pH in normal tissues, by regulating hydrogen ion (H+) flux. The pH is important in cell death under hypoxia, thus a blockade of CA IX results in increased cell death under hypoxia. Therefore, CA IX has become a reliable histochemical marker of hypoxia.
Specifica
| Carbonic Anhydrase IX | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| Q16790 | |
| CA9 | |
| Recombinant Human Carbonic Anhydrase IX/CA9 protein (Gln 38-Asp414). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin) | |
| 005 | |
| Unconjugated | |
| CA9 | |
| Ca9; CA-9; CAIX; CA-IX; Car9; Carbonate dehydratase IX; carbonic anhydrase 9; Carbonic anhydrase IX; carbonic dehydratase; G250; Membrane antigen MN; membrane antigen MN homolog; MN; MN/CA9; P54 / 58N; P54/58N; pMW1; RCC-associated antigen G250; RCC-associated protein G250; renal cell carcinoma-associated antigen G250 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 768 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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