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RACK1 Mouse, Unlabeled, Clone: 20, BD

Mouse Monoclonal Antibody

361.00 CHF - 720.00 CHF

Spezifikation

Antigen RACK1
Klon 20
Konzentration 250μg/mL
Anwendungen Western Blot
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15825309
Unterlagen ansehen Aktionsdetails
BD Biosciences
610177
50 μg
361.00 CHF
1 Set
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Verfügbar ab: 23-05-2024
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15835309
Unterlagen ansehen Aktionsdetails
BD Biosciences
610178
150 μg
720.00 CHF
1 Set
Alternative Produkte anzeigen
Sparen Sie bis zu 
»
Verfügbar ab: 23-05-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

Several proteins which specifically bind to PKC have been classified as RACKs (receptors for activated C-kinase). RACK1 was cloned from a rat brain cDNA expression library by screening for proteins that bind PKC in the presence of phosphatidylserine, diacylglycerol, and calcium in a PKC overlay assay. By sequence homology, RACK1 appears to belong to a superfamily that includes the β subunit of G proteins. All of these proteins contain five to eight internal repeat elements known as WD40 motifs, which appear to have a role in protein-protein interactions. In addition, RACK1 contains two short sequences homologous to a PKC-binding sequence identified in Annexin I and in the brain PKC inhibitor KCIP. The binding of RACK1 to PKC is dose-dependent and occurs at a site on PKC that is distinct from the catalytic domain, indicating that RACK1 is not a PKC substrate.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Spezifikation

Spezifikation

RACK1
250μg/mL
Monoclonal
Mouse
Cell Biology
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
IgM
Affinity Purified
20
Western Blot
Unconjugated
RUO
Bovine, Canine, Chicken, Frog, Human, Mouse, Rat
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Store undiluted at -20°C.
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