missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Disabled-2/p96 Mouse, Unlabeled, Clone: 52, BD
Mouse Monoclonal Antibody
271.78 CHF - 480.43 CHF
Spezifikation
| Antigen | Disabled-2/p96 |
|---|---|
| Klon | 52 |
| Konzentration | 250μg/mL |
| Anwendungen | Western Blot |
| Klassifikation | Monoclonal |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
15835479
|
BD Biosciences
610464 |
50 μg |
 272.00 CHF 271.78 CHF / 1 Set Sparen 0.22 CHF 0.08% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
15845479
|
BD Biosciences
610465 |
150 μg |
481.00 CHF 480.43 CHF / 1 Set Sparen 0.57 CHF 0.12% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
CSF-1 is a growth factor that stimulates the growth and differentiation of immature lymphocytes and is required for the survival of mononuclear phagocytes. Binding of CSF-1 induces dimerization and autophosphorylation of its receptor. This results in the activation of several signal transduction pathways. A unique 96 kDa protein is a component in the CSF-1 signal transduction cascade. p96 is phosphorylated on serine following mitogenic stimulation of a mouse macrophage cell line. p96 contains three potential C-terminal ERK kinase phosphorylation sites, as well as several proline-rich sequences that are potential binding sites for SH3-containing proteins. Structural similarities have been found between p96 and Dab, a product of the Drosophila disabled gene, and p96 was also identified as Disabled-2 (Dab-2) and as differentially expressed in ovarian β receptor to the Smad family of transcription factors. Thus, Dab-2/p96 is an important adaptor molecule in growth factor signaling pathways.
Spezifikation
| Disabled-2/p96 | |
| 250μg/mL | |
| Monoclonal | |
| Mouse | |
| Cell Biology | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| IgG1 | |
| Affinity Purified | |
| Disabled-2 |
| 52 | |
| Western Blot | |
| Unconjugated | |
| RUO | |
| Human, Mouse, Rat | |
| Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at -20°C. |
For Research Use Only.
Haben Sie Verbesserungsvorschläge?Übermitteln Sie eine inhaltliche Korrektur
Berichtigung von Produktinhalten
Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.
Name des Produkts