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ZO-1 Mouse anti-Canine, Human, Mouse, Clone: 1G4A1, Proteintech

Mouse Monoclonal Antibody

Marke:  Proteintech 66452-1-IG-20UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16838345

  • 131.19 CHF / 20 Mikroliter

Verfügbar ab: 28-06-2022
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Beschreibung

Beschreibung

ZO-1 forms complexes with either ZO-2 or ZO-3. In addition, these proteins can also associate with claudin, occludin and F-actin, at tight junction stands, where they provide a linkage between the actin cytoskeleton and the tight junction. ZO-1 expression is significantly reduced in many breast cancer lines. ZO-2 and ZO-3 are ubiquitously expressed within epithelial tight junctions, and unlike ZO-1, which is also expressed at cell junctions of cardiac myocytes, ZO-2 is not expressed in nonepithelial tissue. ZO-1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. ZO-1 may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for the ZO-1 gene. Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
Spezifikation

Spezifikation

ZO-1
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O97758, P39447, Q07157
TJP1
ZO-1 Fusion Protein Ag16454
20 μL
Primary
Mouse, Human, Canine
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence
1G4A1
Unconjugated
TJP1
Tight junction protein 1, Tight junction protein ZO 1, TJP1, ZO 1, ZO1, ZO-1, Zona occludens protein 1, Zonula occludens protein 1
Mouse
Protein G
RUO
21872, 403752, 7082
Antibody
IgG1
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote