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CD3 Mouse anti-Human, Pacific Blue, Clone: UCHT1, BD
Mouse Monoclonal Antibody
Marke: BD Biosciences 558117
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Beschreibung
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
Spezifikation
| CD3 | |
| Monoclonal | |
| 0.2mg/mL | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor | |
| 0.1 mg | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| UCHT1 | |
| Pacific Blue | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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