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VEGF Receptor 3 Rat anti-Mouse, Biotin, Clone: AFL4, eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 13-5988-85

Additional Details : Gewicht : 0.25000kg

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Artikelnummer. 15229989

  • 331.00 CHF / 500 Mikrogramm


Verfügbar ab
17-08-2020
Zum Warenkorb hinzufügen

Beschreibung

Beschreibung

2 μm post-manufacturing filtered. Vascular endothelial growth factor is a key regulator of blood vessel development in embryos and angiogenesis in adult tissues. Unlike VEGF, the related VEGFC stimulates the growth of lymphatic vessels through its specificl ymphatic endothelial receptor VEGFR-3. In 1998, Dumont showed that targeted inactivation of the VEGFR-3 gene in mice resulted in defective blood vessel development in early embryos. Vasculogenesis and angiogenesis occurred, but large vessels became abnormally organized with defective lumens, leading to fluid accumulation in the pericardial cavity and cardiovascular failure at embryonic day 9.5. Thus, VEGFR3 has an essential role in the development of theembryonic cardiovascular system before the emergence of the lymphatic vessels.
Spezifikation

Spezifikation

VEGF Receptor 3
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P35917
FLT41, PCL, FLT4
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
AFL4
Biotin
Flt4
Liquid
Flt4
IgG2a, kappa
500 μg
4° C, store in dark, DO NOT FREEZE!
Primary
14257
Videos
Dokumentation

For Research Use Only.