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ACROBiosystems Unconjugated Human CD47 Protein, His, Avitag™

Unconjugated Protein

Marke:  ACROBiosystems CD7-HA2E9-50UG

Additional Details : Gewicht : 0.00001kg

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Artikelnummer. 15826287

  • 299.38 CHF / 50 Mikrogramm


Verfügbar ab
28-05-2021
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Beschreibung

Beschreibung

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 16.9 kDa. The protein migrates as 33-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Spezifikation

Spezifikation

NP_942088.1
HEK293
Human
16.9 kDa
50 µg
Gln 19 - Pro 139
CD47,MER6,IAP,OA3
Unconjugated
10 mM Bicine, pH8.3
Less than 1.0 EU / µg by the LAL method.
Immune Checkpoint Proteins
Powder
>95% as determined by SDS-PAGE
Unconjugated Human CD47, His,Avitag (CD7-HA2E9) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Pro 139 (Accession # Q08722-3).
-20°C
CD47
His Tag and Avi Tag
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation