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Invitrogen™ UBA2 Monoclonal Antibody (5H11)
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Artikelnummer. 17116753 Alle ansehen Thermo Scientific Produkte
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Menge:
100 μg
Packungsgröße:
100 Mikrogramm
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17116753 100 μg 100 Mikrogramm
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Artikelnummer. 17116753 Lieferant Invitrogen™ Lieferanten-Nr. MA536242

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Mouse Monoclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human K562 whole cell, human Raji whole cell, human THP-1 whole cell, human SW579 whole cell, human HepG2 whole cell, human CCRF-CEM whole cell, rat PC-12 whole cell, mouse RAW2467 whole cell. Flow: A431 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

UBA2 is involved in covalent attachment of one protein to another is one of the more prominent posttranslational modifications in respect to size and ubiquity. Ubiquitin is the most familiar of the protein modifiers and its activation and transfer to target proteins has been studied extensively. Recently, a new group of ubiquitin-like proteins has been receiving a lot of attention. SUMO, or Sentrin, is one of the most intriguing. SUMO has been implicated in the stabilization of target proteins and/or their localization to sub-cellular complexes.The conjugation of SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of the specific E1-activating enzyme SAE1/SAE2, the E2-conjugating enzyme Ubc9, and an E3-like SUMO ligase.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen UBA2
Anwendungen Flow Cytometry, Western Blot
Klassifikation Monoclonal
Klon 5H11
Konzentration 500 μg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 4mg trehalose and 0.05mg sodium azide
Gen UBA2
Gen-Zugriffsnummer Q9UBT2, Q9Z1F9
Gen-Alias AA986091; Anthracycline-associated resistance ARX; Arx; EGK_10449; FLJ13058; HRIHFB2115; SAE2; SUMO1 activating enzyme subunit 2; Sumo-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA1; UBA2; UBA2, ubiquitin-activating enzyme E1 homolog; ubiquitin like modifier activating enzyme 2; ubiquitin-like 1 (sentrin) activating enzyme E1B; ubiquitin-like 1 (sentrin) activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; ubiquitin-like modifier activating enzyme 2; ubiquitin-like modifier-activating enzyme 2; Ubl1a2; Uble1b
Gensymbole UBA2
Wirtsspezies Mouse
Immunogen E. coli-derived human SAE2/UBA2 recombinant protein (Position: E449-K564).
Reinigungsverfahren Affinity chromatography
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 10054, 308508, 50995
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Lyophilized
Isotype IgG2b
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