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  6. Transglutaminase 2/TGM2 Antibody (TGM2/419), Novus Biologicals™

Transglutaminase 2/TGM2 Antibody (TGM2/419), Novus Biologicals™

Codice prodotto. 18600856 Sfoglia Tutto Bio Techne Prodotti
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18600856 0.1 mg 0.10mg
18121029 0.02 mg 0.02mg
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Codice prodotto. 18600856 Fornitore Novus Biologicals N. del fornitore NBP2445940.1mg
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    643.39 CHF
    547.05 CHF / 0.1 Milligramm
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    14% Rabatt
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Verfügbar ab: 26-11-2026
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Description

Mouse Monoclonal Antibody

Transglutaminase 2/TGM2 Monoclonal specifically detects Transglutaminase 2/TGM2 in Human, Monkey, Mouse, Rabbit, Rat samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot.
TRUSTED_SUSTAINABILITY

Specifications

Antigene Transglutaminase 2/TGM2
Applicazioni Immunohistochemistry, Western Blot
Classificazione Monoclonal
Clone TGM2/419
Concentrazione 0.2mg/mL
Coniugato Unconjugated
Diluizione Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Formulazione 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
N. accesso geni P21980
Alias gene C polypeptide, EC 2.3.2.13, G-ALPHA-h, protein-glutamine gamma-glutamyltransferase 2, protein-glutamine-gamma-glutamyltransferase, TG(C), TG2, TGase C, TGase H, TGase-2, TGase-H, TGCGNAH, Tissue transglutaminase, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), Transglutaminase C, Transglutaminase H, Transglutaminase-2
Simboli geni TGM2
Specie ospite Mouse
Immunogeno Recombinant full-length human TGM2 protein
Metodo di purificazione Protein A or G purified
Quantità 0.1 mg
Status giuridico RUO
Disciplina di ricerca Apoptosis, Immune System Diseases, Immunology, Signal Transduction
Primario o secondario Primary
ID gene (immissione) 7052
Test di specificità Recognizes a 77-85kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Target Species Human, Monkey, Mouse, Rabbit, Rat
Content And Storage Store at 4C.
Product Type Antibody
Forma Purified
Isotype IgG2a κ
Linea di prodotti Novus
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