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  6. Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4) 

Invitrogen™ Transferrin Receptor Monoclonal Antibody (H68.4)
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Artikelnummer. 10372703
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500 μg
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1 Stück
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Artikelnummer. 10372703 Lieferant Invitrogen™ Lieferanten-Nr. 136800
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Beschreibung

Mouse Monoclonal Antibody

H68.4 is specific to residues 3-28 of the human transferrin receptor (TfR) tail.

Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients.
TRUSTED_SUSTAINABILITY

Spezifikation

Antigen Transferrin Receptor
Anwendungen ELISA, Immunohistochemistry (Paraffin), Immunomicroscopy, Immunoprecipitation, Western Blot, Immunocytochemistry
Klassifikation Monoclonal
Klon H68.4
Konzentration 0.5 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 0.1% sodium azide; pH 7.4
Gen TFRC
Gen-Zugriffsnummer P02786, Q07891, Q62351, Q90997, Q99376
Gen-Alias 2610028K12Rik; AI195355; AI426448; AU015758; CD antigen CD71; CD71; chicken transferrin receptor; E430033M20Rik; I79_000642; IMD46; mammary tumor virus receptor 1; Mtvr1; Mtvr-1; p90; sTfR; T9; TfR; tfR1; TFR2; TFRC; TR; transferrin receptor; transferrin receptor (p90, CD71); transferrin receptor 2; transferrin receptor protein 1; Transferrin receptor protein 1, serum form; Trfr
Gensymbole TFRC
Wirtsspezies Mouse
Immunogen Recombinant human transferrin receptor.
Reinigungsverfahren Affinity chromatography
Menge 100 μg
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 100689395, 22042, 396191, 64678, 7037
Zielspezies Chicken, Hamster, Human, Mouse, Rat
Inhalt und Lagerung -20°C
Produkttyp Antibody
Form Liquid
Isotype IgG1
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