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TNF Rat anti-Mouse, PE, Clone: MP6-XT22, BD

Rat Monoclonal Antibody

149.00 CHF - 496.00 CHF

Spezifikation

Antigen TNF
Klon MP6-XT22
Konzentration 0.2mg/mL
Anwendungen Flow Cytometry
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15810739
Unterlagen ansehen Aktionsdetails
BD Biosciences
561063
25 μg
149.00 CHF
1 Stück
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Verfügbar ab: 22-04-2024
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15817688
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BD Biosciences
554419
0.1 mg
496.00 CHF
1 Stück
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Sparen Sie bis zu 
»
Verfügbar ab: 22-04-2024
Sie sich ein, um den Lagerbestand zu sehen
Zum Warenkorb hinzufügen
 
Beschreibung

Beschreibung

The MP6-XT22 antibody specifically binds to mouse Tumor Necrosis Factor (TNF, also known as TNF-α). TNF is produced by many activated cell types including monocytes, macrophages, astrocytes, granulocytes, mast cells, T and B lymphocytes, NK cells, keratinocytes, fibroblasts, adipocytes, and certain tumor cells. Activated cells express type II transmembrane TNF glycoproteins that associate as homotrimeric complexes. After enzymatic cleavage, the extracellular regions of membrane TNF are shed as soluble homotrimers. TNF is a potent multifunctional cytokine that can exert regulatory and cytotoxic effects on a wide range of normal lymphoid and non-lymphoid cells and tumor cells. Although TNF serves as a primary mediator in protective immune responses against microbial and viral pathogens, it can also drive systemic pathophysiologic responses including septic shock, cachexia and autoimmune diseases. Mouse TNF exerts its biological activities by binding and signaling through cell surface membrane Type I and Type II TNF Receptors (aka, TNFRI/CD120a and TNFRII/CD120b, respectively).

Spezifikation

Spezifikation

TNF
0.2mg/mL
Monoclonal
Rat
Mouse
IgG1
Affinity Purified
MP6-XT22
Flow Cytometry
PE
RUO
Aqueous buffered solution containing ≤0.09% sodium azide.
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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