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TIGIT Monoclonal Antibody (MBSA43), PE-eFluor™ 610, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Marke:  Invitrogen 61950042

Additional Details : Gewicht : 0.01000kg

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Artikelnummer. 15983324

  • 494.00 CHF / 100 Stück
Verfügbar ab: 11-04-2024
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Beschreibung

Beschreibung

Description: The MBSA43 monoclonal antibody reacts with human T cell immunoreceptor with Ig and ITIM domains (TIGIT), which is also known as VSTM3 or WUCAM. This 26 kDa protein is a member of the poliovirus receptor (PVR) family. The expression of TIGIT has been reported on NK cells, regulatory T cells, follicular T helper cells, memory CD4+ T cells, and CD8+ T cells, but it is not expressed on B cells or naive CD4+ T cells. TIGIT may be upregulated on naive CD4+ T cells upon activation. TIGIT can interact with certain members of the PVR and PVR-like families, including CD155, and also mediates the interaction of NK and T cells with antigen presenting cells, fibroblasts, and endothelial cells that express PVR and PVR-like proteins. MBSA43 is reported to crossreact with Rhesus macaque. Applications Reported: This MBSA43 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MBSA43 antibody has been pre-titrated and tested by flow cytometeric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. PE-eFluor™ 610 can be excited with laser lines from 488-561 nm and emits at 607 nm. We recommend using a 610/20 band pass filter (equivalent to PE-Texas Red™).

TIGIT Monoclonal antibody specifically detects TIGIT in Human samples. It is validated for Flow Cytometry.
Spezifikation

Spezifikation

TIGIT
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q495A1
TIGIT
Affinity chromatography
RUO
201633
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
MBSA43
PE-eFluor 610
TIGIT
ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote