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ThPOK Monoclonal Antibody (2POK), PE, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

147.00 CHF - 431.00 CHF

Spezifikation

Antigen ThPOK
Klon 2POK
Konzentration 0.2 mg/mL
Anwendungen Flow Cytometry
Klassifikation Monoclonal
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Produkte 2
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
Produktcode Marke Menge Preis Menge & Verfügbarkeit  
15228919
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Affymetrix eBioscience
12-5928-82
100 μg
431.00 CHF
100 Mikrogramm
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Verfügbar ab: 08-05-2024
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15218919
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Affymetrix eBioscience
12-5928-80
25 μg Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11.
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Beschreibung

Beschreibung

Description: This 2POK monoclonal antibody reacts with mouse ThPOK, which is also known as c-Krox and Zbtb7b. In hematopoietic cells, this 78 kDa transcription factor is expressed in thymocytes and T lymphocytes in the spleen and lymph nodes. In non-hematopoietic cells, ThPOK can be detected in the skin, heart, smooth muscle, and liver. Studies demonstrate that ThPOK promotes CD4+ lineage differentiation by inhibiting the expression of CD8 lineage-specific genes such as Runx3. ThPOK has also been shown to inhibit Cd4 silencing, another key facet required for differentiation to the CD4+ lineage. In addition to its role in thymocyte development, ThPOK is involved in the effector functions of invariant natural killer T (iNKT) cells and gamma delta T cells. Applications Reported: This 2POK antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This 2POK antibody has been tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat. 00-5523) and protocol. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes (e.g., COL1A1; MIM 120150) and has a role in development.
Spezifikation

Spezifikation

ThPOK
0.2 mg/mL
Monoclonal
Liquid
RUO
Q64321
Zbtb7b
Primary
4° C, store in dark, DO NOT FREEZE!
Zbtb7b
2POK
Flow Cytometry
PE
Rat
Mouse
22724
IgG2a κ
Affinity chromatography
Antibody
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Product Certifications

For Research Use Only.