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Invitrogen™ Human MMP-14 (Catalytic Domain) Recombinant Protein

Recombinant Protein

Marke:  Invitrogen™ RP77531

Additional Details : CAS : 69-74-9 Gewicht : 1.24740kg

Artikelnummer. 11539081

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Beschreibung

Beschreibung

MMP14 Recombinant Protein, RP-77531, from Invitrogen.

RP-77531 is a purified recombinant MMP-14 (catalytic domain) protein, expressed in E.coli. MT1-MMP catalytic domain is produced by activation of a recombinant soluble proform of MT1-MMP purified from E. coli periplasm. The sequence spans Tyr89-Gly265 of mature human MT1-MMP. The catalytic domain consists of 177 amino acids with a calculated MW of 20kDa. The specific activity of this domain is >150mU/mg, where 1U hydrolyzes 1μmol peptide within 1 minute. The catalytic domain is inhibited by tissue inhibitors of matrix metalloproteinases 2 and 3 (TIMP-2 and TIMP-3) and by chelators of divalent cations like EDTA or o-phenanthroline. This product can be used to study the activation of TIMP-2 and the degradation of proteins of the extracellular matrix. The enzyme allows screening of TIMP inhibitors and characterization of inhibitor action.
Spezifikation

Spezifikation

P50281
TBS with 5mM CaCl2 and no preservative; pH 7.5
∽20
7.5
E. coli
RUO
Human MMP14
Human
Hu
Recombinant
Recombinant
Control
4323
Human MMP14
10μg
-80°C
MT1-MMP
MMP14
Unconjugated
E. coli
Liquid
purified
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Zertifikate
Sonderangebote

Sonderangebote

in vitro research only