Learn More
Beschreibung
2'-OMe-Bz-A CEP is a phosphoramidite containing 5' DMT and the nucleoside adenosine (A) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in an amber bottle.
Available with a Serum Vial, 20-400 Finish, or 28-400 Finish neck style.
- Serum vial neck style is compatible with most Applied Biosystems synthesizers and AKTA synthesizers.
- 20-400 finish neck style is compatible with most Expedite synthesizers.
- 28-400 finish neck style is compatible with most MerMade synthesizers.
Features:
- Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-O-methyl-adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
- Molecular formula—C48H54N7O8P
- Base—A
- Base Protection—Bz
- Formula weight—887.97 g/mol
- CAS number—110782-31-5
- HPLC purity—≥99%; M-11 Impurity: ≤0.01%; Single critical impurity ≤0.3%
- 31P NMR purity—>99%; Sum of non-primary peaks at 140-152ppm ≤0.5%
Spezifikation
Spezifikation
| Format | Amber Bottle (20-400 Thread) |
| Zur Verwendung mit (Geräte) | Expedite Synthesizers |
| Produkttyp | 2in-OMe-Bz-A CEP |
| Inhalt und Lagerung | Im Tiefkühlgerät lagern (bei oder unter -20 °C). |
| Nukleosidtyp | Adenosine (A) |
| Reagenzienfunktionen | 2in-OMe modified |
| Versandbedingung | Raumtemperatur |
| Reinheit | 99% |
| Menge | 1 g |
| Reagenztyp | Phosphoramidit |
| Mehr anzeigen |
For Research Use Only.
Indem Sie auf Absenden klicken, erklären Sie sich damit einverstanden, dass Fisher Scientific sich mit Ihnen in Verbindung setzen kann, um Ihr Feedback in diesem Formular zu bearbeiten. Wir werden Ihre Informationen nicht für andere Zwecke weitergeben. Alle bereitgestellten Kontaktinformationen werden in Übereinstimmung mit unserer Datenschutzrichtlinie aufbewahrt. Datenschutzrichtlinie.