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Thermo Scientific™ Tango™ AGTRL1-bla U2OS Cells

Codice prodotto. 10713484
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Quantità:
8 x 106 Cells
Dimensione della confezione:
Pezzo
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Codice prodotto. Quantità Dimensione della confezione
10713484 8 x 106 Cells Pezzo
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Codice prodotto. 10713484 Fornitore Thermo Scientific™ N. del fornitore K1754

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Descrizione

The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

The Tango™ AGTRL1-bla U2OS cells contain the human Angtiotension-Like Receptor 1 (AGTRL1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ AGTRL1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of established ligands. In addition, Tango™AGTRL1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary for each product.

TRUSTED_SUSTAINABILITY

Specifica

Numero di accesso NM_005161
Assay Entry Cell-based beta-arrestin recruitment
Cell State Dividing Cells
Content And Storage LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ AGTRL1-bla U2OS cells
• Tango™ AGTRL1-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ AGTRL1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Cytoplasmic Tail Native Tail
Metodo di rilevamento Fluorescence
Da utilizzare con (applicazione) GPCRs
Simbolo del gene AGTRL1
Include AGTRL1-bla U2OS cells, AGTRL1-bla U2OS Assay Protocol, Certificate of Analysis
Population Status Single Cell Clone Origin
Linea di prodotti GeneBLAzer
Famiglia di proteine GPCR (G-Protein Coupled Receptors)
Quantità 8 x 106 Cells
Readout End Point
Gene reporter BLA (Beta-Lactamase)
Target Entry AGTRL1
Tipo Dividing Cells
Linea cellulare U2OS
System Type Tango™
Druggable Target GPCR
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For Research Use Only. Not for use in diagnostic procedures.

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