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Gibco™ Human FRP-5 (soluble) Recombinant Protein, PeproTech®

Codice prodotto. 17800653
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Codice prodotto. Quantità Dimensione della confezione
17800653 100 μg 100µg
17889992 10 μg 10µg
17821443 1 mg 1mg
17871023 250 μg 250µg
17830183 500 μg 500µg
17811333 50 μg 50µg
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Codice prodotto. 17800653 Fornitore Gibco™ N. del fornitore 12053100UG
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Verfügbar ab: 04-12-2026
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Descrizione

Recombinant Protein

PeproTech's CHO cell-derived Recombinant Human sFRP5 is a 288-amino-acid length glycoprotein with a calculated molecular weight of 32.7 kDa; however, due to glycosylation, protein migration occurs at an apparent molecular weight of approximately 33-35 kDa by SDS-PAGE analysis under both reducing and non-reducing conditions. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Secreted frizzled-related protein 5 (SFRP5) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. SFRP5 and SFRP1 may be involved in determining the polarity of photoreceptor cells in the retina. SFRP5 is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.
TRUSTED_SUSTAINABILITY

Specifica

Numero di accesso Q5T4F7
Da utilizzare con (applicazione) Bioactivity, Control
Formulazione Protein with no preservative
ID gene (immissione) 6425
Peso molecolare 32.7 kDa
Nome Human FRP-5 (soluble)
Metodo di purificazione Purified
Quantità 100 μg
Sorgente CHO cells
Requisiti di stoccaggio -20°C
Status giuridico RUO
Concentrazione di endotossine <1 EU/μg
Alias gene AI605071; Frizzled-related protein 1b; FRP1B; FRP-1b; SARP3; SARP-3; secreted apoptosis related protein 3; secreted apoptosis-related protein 3; secreted frizzled related protein 5; secreted frizzled-related protein 5; secreted frizzled-related sequence protein 5; SFRP5; sFRP-5
Nome comune SFRP5
Simbolo del gene SFRP5
Attività biologica Determined by its ability to decrease alkaline phosphatase activity in CCL-226 cells when treated with 25 ng/ml of Murine Wnt-3 a.
Product Type Protein
Coniugato Unconjugated
Recombinant Recombinant
Sequenza EEYDYYGWQA EPLHGRSYSK PPQCLDIPAD LPLCHTVGYK RMRLPNLLEH ESLAEVKQQA SSWLPLLAKR CHSDTQVFLC SLFAPVCLDR PIYPCRSLCE AVRAGCAPLM EAYGFPWPEM LHCHKFPLDN DLCIAVQFGH LPATAPPVTK ICAQCEMEHS ADGLMEQMCS SDFVVKMRIK EIKIENGDRK LIGAQKKKKL LKPGPLKRKD TKRLVLHMKN GAGCPCPQLD SLAGSFLVMG RKVDGQLLLM AVYRWDKKNK EMKFAVKFMF SYPCSLYYPF FYGAAEPH
Content And Storage -20°C
Attività Determined by its ability to decrease alkaline phosphatase activity in CCL-226 cells when treated with 25 ng/ml of Murine Wnt-3a.
Sistema di espressione CHO cells
Forma Lyophilized
Purity or Quality Grade ≥ 98% by SDS-PAGE gel and HPLC analyses.
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