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SRRM1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 12822-1-AP-20UL
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Beschreibung
This antibody is a rabbit polyclonal antibody raised against residues near the N terminus of human SRRM1.
Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3′-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.Spezifikation
| SRRM1 | |
| Polyclonal | |
| Unconjugated | |
| SRRM1 | |
| 160 KD, POP101, SRM160, SRRM1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10250, 313620, 51796 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.3 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q52KI8, Q8IYB3 | |
| Srrm1 | |
| SRRM1 Fusion Protein Ag3513 | |
| 20 μL | |
| Primary | |
| Mouse, Human, Rat | |
| Antibody | |
| IgG |
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