Invitrogen™ Somatostatin Monoclonal Antibody (7G5)

Beschreibung

MA5-17182 targets SST in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human samples. The MA5-17182 immunogen is purified recombinant fragment of human SST (amino acids: 1-116) expressed in E. Coli. MA5-17182 detects SST which has a predicted molecular weight of approximately 12.7kDa.

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.