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R&D Systems™ SN 38

Artikelnummer. 18782664
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50 Milligramm
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Artikelnummer. 18782664 Lieferant R&D Systems™ Lieferanten-Nr. 2684/10
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    193.20 CHF / 10 Milligramm
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Verfügbar ab: 30-10-2026
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Beschreibung

A Tocris product, part of R&D Systems. DNA topoisomerase I inhibitor; antitumor

Active metabolite of CPT-11 (Cat. No. 2688) that inhibits DNA topoisomerase I (IC50 values are 0.74 and 1.9 μM in P388 and Ehrlich cells respectively). Inhibits DNA and RNA synthesis (IC50 values are 0.077 and 1.3 μM respectively) but does not affect protein synthesis. Displays potent antitumor activity against a range of human tumor cell lines (IC50 values are 3.3, 13, 19 and 22 nM for HCT-116, BEL-7402, HL60 and HELA cells respectively).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 86639-52-3
Summenformel C22H20N2O5

Specifications

Chemischer Name oder Material SN 38
Menge 10 mg
Produktlinie Tocris
Formelmasse 392.4
Reinheit >98%
Molekulargewicht 392.411
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