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IL6 Recombinant Human Protein, Invitrogen™ Sino Biological™
This recombinant protein is expressed from a DNA sequence encoding the mature form of human IL6 (NP_000591.1) (Val 30-Met 212) retaining the initial Met at the N-terminus
110.00 CHF - 530.00 CHF
Spezifikation
Zur Verwendung mit (Anwendung) | Protein Expression and Isolation, Enzyme and Protein Activity Assay, Protein Assay Control, Reference Standards and Accessories |
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Molekulargewicht | 20.3kDa |
Lagerungsbedingungen | Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed. |
Strukturform | Full Length/Recombinant |
Gen-Alias | BSF2, HGF, HSF, IFNB2, IL-6 |
Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
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Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
13453009
|
Invitrogen
10395HNAE5 |
5μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
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13433009
|
Invitrogen
10395HNAE25 |
5 x 5μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
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13463009
|
Invitrogen
10395HNAE50 |
50μg |
Dieser Artikel wurde eingestellt und ist leider nicht mehr verfügbar. Sehen Sie sich das Produkt an, um alternative Produktvorschläge zu sehen oder kontaktieren Sie unseren Technischen Support unter 056 618 41 11. |
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Beschreibung
Interleukin 6 (IL-6) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.Background: Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, and is known particularly for its role in the immune response and acute phase reactions. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity. IL-6 is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule with the molecular mass of 22-28kDa. Three IL-6 signaling pathways (STAT1, STAT3, and Ras-dependent MAPK cascade) have been reported. Dysregulated production of IL-6 and IL6R are implicated in the pathogenesis of several inflammatory diseases and malignancies such as multiple myeloma, rheumatoid arthritis, or osteoporosis.
- N-terminal Sequence Analysis: Met
- Activity: 1. Measured by its binding ability in a functional ELISA; immobilized recombinant human IL6 (100μL/well of a 8μg/mL solution) has been shown to bind recombinant human IL6R with a linear range of 1.25-20.0ng/mL; 2. Measured in a cell proliferation assay using TF1 human erythroleukemic cells, the EC50 for this effect is typically 0.2-0.8ng/mL
- Formulation: lyophilized in 140mM NaCl, 2.7mM KCl, 10mM Na2HPO4, 1.8mM KH2PO4, pH 7.4, 5% mannitol, 5% trehalose, 0.02% Tween™-80
- Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2mg/mL or lower; aliquot and use as soon as possible
Manufactured by Sino Biological (China).
Spezifikation
Protein Expression and Isolation, Enzyme and Protein Activity Assay, Protein Assay Control, Reference Standards and Accessories | |
Store at -20°C. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles. Expires one year from date of receipt when stored as instructed. | |
BSF2, HGF, HSF, IFNB2, IL-6 | |
IL6 | |
E. coli | |
Lyophilized | |
≥95% by SDS-PAGE |
20.3kDa | |
Full Length/Recombinant | |
Interleukin 6 (interferon, beta 2) | |
Untagged | |
Cytokines & Receptors | |
Interleukins |
For Research Use Only. Not for use in diagnostic procedures.