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  5. R&D Systems™ SB 202190

R&D Systems™ SB 202190

Code produit 30001220
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Code produit Quantité Conditionnement
30001220 10 mg 10mg
18054982 50 mg 50mg
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Code produit 30001220 Fournisseur R&D Systems™ Code fournisseur 1264/10
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Descrizione

A Tocris product, part of R&D Systems. Potent, selective inhibitor of p38 MAPK

SB 202190 is a highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively). Promotes stability of naive human pluripotent stem cells in culture. Inhibits Yamanaka factor reprogramming of human fibroblasts to iPSCs. SB 202190 improves the self-renewal ability of neuronal stem cells from NPC1-deficient mice.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 152121-30-7
Formule moléculaire C20H14FN3O

Specifica

Nom chimique ou matériau SB 202190
Quantité 10 mg
Gamme de produits Tocris
Poids de la formule 331.35
Pureté >99%
Poids moléculaire 331.35
Titolo del prodotto
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