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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera Recombinant Protein

Codice prodotto. 17986241
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità Dimensione della confezione
17986241 100 μg 100µg
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Codice prodotto. 17986241 Fornitore Invitrogen™ N. del fornitore RP88398
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    532.00 CHF
    404.32 CHF / 100 Mikrogramm
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Verfügbar ab: 16-12-2026
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Descrizione

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Specifica

Da utilizzare con (applicazione) Binding Assay, Control, ELISA Standard
Formato Lyophilized
Formulazione PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Peso molecolare 51.54 kDa
Nome SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera
Intervallo di pH 7.4
Metodo di purificazione Purified
Quantità 100 μg
Requisiti di stoccaggio -20°C, Avoid Freeze/Thaw Cycles
Status giuridico RUO
Concentrazione di endotossine <1.0 EU/μg
Alias gene Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Nome comune SARS-CoV-2 Spike Protein RBD
Attività biologica The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Product Type Protein
Coniugato Unconjugated
Recombinant Recombinant
Tag proteine Fc-tag
Sequenza SARS-CoV-2 spike RBD (Accession # YP_009724390.1), amino acids Arg319-Phe541 with a V367F substitution and a C-terminal mouse IgG1 Fc region
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Attività The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Sistema di espressione HEK293 cells
Forma Lyophilized
Purity or Quality Grade >90% as determined by SDS-PAGE.
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