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Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera Recombinant Protein

Code produit 17986241
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Quantité:
100 μg
Conditionnement:
100µg
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Code produit Quantité Conditionnement
17986241 100 μg 100µg
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Code produit 17986241 Fournisseur Invitrogen™ Code fournisseur RP88398
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Verfügbar ab: 16-12-2026
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Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (400 μL) be added to the vial to prepare a stock solution of 0.25 mg/mL. Concentration is measured by UV.

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.
TRUSTED_SUSTAINABILITY

Specifications

À utiliser avec (application) Binding Assay, Control, ELISA Standard
Format Lyophilized
Formule PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
Poids moléculaire 51.54 kDa
Nom SARS-CoV-2 Spike Protein (RBD) (V367F) Fc Chimera
Plage de pH 7.4
Méthode de purification Purified
Quantité 100 μg
Conditions de stockage -20°C, Avoid Freeze/Thaw Cycles
État réglementaire RUO
Concentration en endotoxines <1.0 EU/μg
Alias de gène Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
Nom usuel SARS-CoV-2 Spike Protein RBD
Activité biologique The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Type de produit Protein
Conjugué Unconjugated
Recombinant Recombinant
Marqueur de protéine Fc-tag
Séquence SARS-CoV-2 spike RBD (Accession # YP_009724390.1), amino acids Arg319-Phe541 with a V367F substitution and a C-terminal mouse IgG1 Fc region
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Activité The SARS-CoV-2 (2019-nCoV) Spike RBD-mFc (V367F) Recombinant Protein can bind with Human ACE2 in functional ELISA assay.
Système d’expression HEK293 cells
Forme Lyophilized
Pureté ou qualité >90% as determined by SDS-PAGE.
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