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Rubicon Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marke:  Proteintech 21444-1-AP-150UL

Additional Details : Gewicht : 0.00010kg

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Artikelnummer. 16841035

  • 351.68 CHF / 150 Mikroliter

Verfügbar ab: 01-07-2022
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Beschreibung

Beschreibung

Two Beclin-1-interacting proteins, the run domain Beclin-1 interacting and cysteine-rich containing protein (Rubicon) and ATG14L, reciprocally regulate autophagy at different stages. Knockdown of Rubicon caused enhancement of autophagy while that of ATG14L caused a defect in autophagosome formation. Rubicon functions as part of a Beclin-1-PIK3C3-containing autophagy complex and is also an essential, positive regulator of the NAPDH oxidase complex. Upon microbial infection or TLR2 activation, Rubicon interacts with the CYBA subunit of the NAPDH oxidase complex, leading to a burst of reactive oxygen species and inflammatory cytokines.
Spezifikation

Spezifikation

Rubicon
Polyclonal
Unconjugated
RUBCN
Baron, KIAA0226, RUBCN, Rubicon
Rabbit
Antigen Affinity Chromatography
RUO
100502698, 303885, 9711
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
0.47 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q80U62, Q92622
Rubcn
Rubicon Fusion Protein Ag13715
150 μL
Primary
Human, Mouse, Rat
Liquid
Videos
Sicherheitsdatenblatt (SDS)
Dokumentation
Zertifikate
Sonderangebote

Sonderangebote