missing translation for 'onlineSavingsMsg'
Learn More
Learn More
R&D Systems™ Recombinant Human ICOS Fc Chimera Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Marke: R&D Systems™ 169-CS-050
Additional Details : Gewicht : 0.00970kg
Beschreibung
Measured by its ability to inhibit human T cell proliferation induced by rhB7-H2/Fc Chimera in the presence of anti-CD3. Wang, S. et al. (2000) Blood 96:2808. The ED50 for this effect is 1-4 μg/mL in the presence of 3 μg/mL Recombinant Human B7-H2 Fc Chimera (Catalog # 165-B7 ) and at least 20 ng/mL of anti-CD3. Optimal dilutions should be determined by each laboratory for each application.Spezifikation
Q9Y6W8 | |
Lyophilized from a 0.2 μm filtered solution in PBS. | |
M.W. (Observed): 50-60 kDa, reducing conditions; M.W. (theoretical): 40.3 kDa (monomer) | |
50 μg | |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
<0.10 EU / 1 μg of the protein by the LAL method. | |
Unconjugated | |
Reconstitute at 100 μg/mL in sterile PBS. | |
ICOS |
Bioactivity | |
29851 | |
ICOS Fc Chimera | |
Mouse myeloma cell line, NS0-derived human ICOS protein Human ICOS (Glu21-Phe141) (N-terminus) Accession # Q9Y6W8 IEGRMD Human IgG1 (Pro100-Lys330) (C-terminus) | |
Disulfide-linked homodimer | |
ICOS | |
Recombinant | |
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain. |