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Thermo Scientific™ (R,R)-Chloramphenicol, 98%
(R,R)-Chloramphenicol, CAS # 56-75-7, also known as chloromycetin, is a compound with broad-spectrum antibiotic and bacteriostatic activities.
43.58 CHF - 137.43 CHF
Chemische Identifikatoren
| CAS | 56-75-7 |
|---|---|
| Summenformel | C11H12Cl2N2O5 |
| Molekulargewicht (g/mol) | 323.126 |
| MDL-Nummer | MFCD00078159 |
| InChI-Schlüssel | WIIZWVCIJKGZOK-RKDXNWHRSA-N |
| PubChem CID | 5959 |
| ChEBI | CHEBI:17698 |
| IUPAC-Name | 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide |
| SMILES | C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|---|---|---|---|---|---|---|---|---|---|
| Produktcode | Marke | Menge | Preis | Menge & Verfügbarkeit | |||||
|
11445786
|
Thermo Scientific™
B20841.14 |
25g |
 44.80 CHF 43.58 CHF / 25 Gramm Sparen 1.22 CHF 2% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
|
11455786
|
Thermo Scientific™
B20841.22 |
100g |
142.00 CHF 137.43 CHF / 100 Gramm Sparen 4.57 CHF 3% Rabatt |
Log in om dit product te kopen Registreer vandaag om een webaccount aan te maken | |||||
Beschreibung
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
- (R,R)-chloramphenicol is a compound with antibiotic and bacteriostatic activity and is derived from Streptomyces venequelae
- It that can block the translation on the 50S subunit at the peptidyltransferase step. The binding affects the peptidyl transferase activity, preventing the transfer of amino acids to the growing peptide chains and inhibiting peptide bond formation. The resulting inhibition of the bacterial protein synthesis impedes bacterial cell proliferation
Application
- (R,R)-chloramphenicol has been used for several molecular biology approaches, mainly for bacterial selection. It can be used to select transformed cells containing chloramphenicol resistance genes
- This compound can also promote mitochondrial and chloroplast protein synthesis and the ribosomal formation of (p)ppGpp, depressing the rRNA transcription process
- In vitro results demonstrate that (R,R)-chloramphenicol shows activity against several vancomycin-resistant E. faecium strains
Chemische Identifikatoren
| 56-75-7 | |
| 323.126 | |
| WIIZWVCIJKGZOK-RKDXNWHRSA-N | |
| CHEBI:17698 | |
| C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] |
| C11H12Cl2N2O5 | |
| MFCD00078159 | |
| 5959 | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide |
Spezifikation
| Chloramphenicol | |
| 0.99 | |
| MFCD00078159 | |
| 14,2077 | |
| WIIZWVCIJKGZOK-RKDXNWHRSA-N | |
| 2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide | |
| 5959 | |
| 323.14 |
| 56-75-7 | |
| C11H12Cl2N2O5 | |
| 2225532 | |
| Soluble in alcohol,propylene,glycol,acetone and ethyl acetate. Slightly soluble in water. | |
| C1=CC(=CC=C1C(C(CO)NC(=O)C(Cl)Cl)O)[N+](=O)[O-] | |
| 323.126 | |
| CHEBI:17698 | |
| ≥99% |
Sicherheit und Handhabung
GHS H Statement
H350-H361
P201-P202-P281-P308+P313-P501c
H350
missing translation for 'einecsNumber' : 200-287-4
missing translation for 'rtecsNumber' : AB6825000
missing translation for 'tsca' : Yes
Produktidentifikator
Signalwort
Gefahrenkategorie
Gefahrenhinweis
Sicherheitshinweis
Ergänzende Informationen
- (R,R)-Chloramphenicol
Signalwort
- Gefahr
Gefahrenkategorie
- Karzinogenität Kategorie 1B
Gefahrenhinweis
- H350-Kann Krebs erzeugen.
Sicherheitshinweis
- P201-Vor Gebrauch besondere Anweisungen einholen.
- P308+P313-BEI Exposition oder falls betroffen: Ärztlichen Rat einholen/ärztliche Hilfe hinzuziehen.
Ergänzende Informationen
- MIXTURE LIST-Enthält: Chloramphenicol
RUO – Research Use Only
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