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  5. STEMCELL Technologies Purmorphamine

STEMCELL Technologies Purmorphamine

Artikelnummer. 17130042
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Menge:
1 mg
5 mg
Unit Size:
5 Milligramm
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17130042 5 mg 5 Milligramm
17120042 1 mg -
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Product Code. 17130042 Supplier STEMCELL Technologies Supplier No. 72204

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Description

Hedgehog pathway activator; Activates Smoothened

  • Purmorphamine is a tri-substituted purine derivative that activates the Hedgehog pathway by directly binding to and activating the Hedgehog receptor Smoothened (EC50 = 1 μM)
  • (Sinha and Chen)
  • Promotes differentiation of ventral spinal progenitors and motor neurons from human pluripotent stem cells (Hu and Zhang, Karumbayaram et al.), Li et al.)
  • Promotes differentiation of osteoblasts from human and mouse mesenchymal cells (Beloti et al.), Wu et al. 2002, Wu et al.) 2004)
  • Inhibits differentiation and maturation of adipocytes from human mesenchymal cells (Fontaine et al.)

Specifications

CAS 483367-10-8
Menge 5 mg
Summenformel C31H32N6O2
Reinheit ≥ 98%
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