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Invitrogen™ Protein APC Polyclonal Antibody
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Artikelnummer. 16323015
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Menge:
100 μL
Unit Size:
100 Mikroliter
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16323015 100 μL 100 Mikroliter
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Product Code. 16323015 Supplier Invitrogen™ Supplier No. PA586107

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Rabbit Polyclonal Antibody

Purity is > 95% by SDS-PAGE.

This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Protein APC
Anwendungen Immunohistochemistry (Paraffin), Western Blot
Klassifikation Polyclonal
Konzentration 1 mg/mL
Konjugat Unconjugated
Zusammensetzung PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gen Apc
Gen-Zugriffsnummer P25054, P70478, Q61315
Gen-Alias adenomatosis polyposis coli; adenomatosis polyposis coli tumor suppressor; adenomatous polyposis coli; adenomatous polyposis coli protein; AI047805; APC; APC, WNT signaling pathway regulator; AU020952; AW124434; BTPS2; CC1; Deleted in polyposis 2.5; DP2; DP2.5; DP3; FAP; FPC; GS; mAPC; Min; multiple intestinal neoplasia; PPP1R46; Protein APC; protein phosphatase 1, regulatory subunit 46; RATAPC; truncated adenomatosis polyposis coli; WNT signaling pathway regulator
Gensymbole Apc
Wirtsspezies Rabbit
Immunogen Synthetic peptide, corresponding to the C-terminal of Human APC.
Reinigungsverfahren Antigen Affinity Chromatography
Menge 100 μL
Regulatorischer Status RUO
Primär oder sekundär Primary
Gen-ID (Entrez) 11789, 24205, 324
Zielspezies Human, Mouse, Rat
Inhalt und Lagerung Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Produkttyp Antibody
Form Liquid
Isotype IgG
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