PNP Polyclonal Antibody, Invitrogen™

Beschreibung

Immunogen sequence: YTYEDYKNTA EWLLSHTKHR PQVAIICGSG LGGLTDKLTQ AQIFDYGEIP NFPRSTVPGH AGRLVFGFLN GRACVMMQGR FHMYEGYPLW KVTFPVRVFH LLGVDTLVVT NAAGGLNPKF EVGDIMLIRD HINLPGFSGQ NPLRGPNDER GAPHR Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.

This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants.