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Invitrogen™ Human PIP5K1C, GST Tag Recombinant Protein

Artikelnummer. 17138855
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Menge:
1 mg
100 μg
20 μg
Packungsgröße:
1 Milligramm
100 Mikrogramm
20 Mikrogramm
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Artikelnummer. Menge unitSize
17138855 1 mg 1 Milligramm
15950423 20 μg 20 Mikrogramm
17188825 100 μg 100 Mikrogramm
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Artikelnummer. 17138855 Lieferant Invitrogen™ Lieferanten-Nr. A33742

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Beschreibung

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. This PIP5K1C recombinant human protein (full length) was expressed in insect cells. PIP5K1C recombinant human protein is also available in our SelectScreen™ Kinase Profiling Service. Validated for use with the Adapta™ assay Available in multiple pack sizes for convenient use Also available in our SelectScreen Kinase Profiling Service Protein Form: Full Length, Recombinant, Active The gene accession number for PIP5K1C is NP_036530.1.

PIP5K1C lipid kinase or phosphatidylinositol-4-phosphate 5-kinase 1 gamma phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1C is found at synapses and has been found to play roles in endocytosis and cell migration. PIP5K1C directly associates with β-catenin and increases β-catenin activity downstream of growth factor stimulation. PIP5K1C expression and kinase activity enhance β-catenin phosphorylation on residues that promote nuclear importation and transcriptional activity. PIP5K1C deficiency impairs neutrophil recruitment as a result of defect in adhesion. PIP5K1C regulated the adhesion through facilitation of RhoA GTPase and integrin activation by chemoattractants.
  • Validated for use with the Adapta™ assay
  • Available in multiple pack sizes for convenient use
TRUSTED_SUSTAINABILITY

Spezifikation

Zugriffsnummer NP_036530.1
Zur Verwendung mit (Anwendung) Kinase Assay
Molekulargewicht 99.6 kDa
Menge 1 mg
Kinase-Familie PI3 Kinase
Proteinlänge Full Length
Spezies Human
Rekombinant Recombinant
Proteinmarkierung GST Tag
Inhalt und Lagerung Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol
Versandbedingung Dry Ice
Expressionssystem Insect
Proteinform Full Length, Recombinant, Active
Form Liquid
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