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Invitrogen™ Human PIK3C3 (hVPS34), GST Tag Recombinant Protein
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Menge:
100 μg
20 μg
Packungsgröße:
1 Stück
100 Mikrogramm
Beschreibung
For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.
PIK3C3 (hVPS34) is the sole class III member of the PI3 Kinase family. PIK3C3 phosphorylates phosphatidylinositol (PI) to produce phosphatidylinositol 3-phosphate [PI(3)P], which recruits downstream effectors containing FYVE and Phox domains to membranes. PIK3C3 is involved in coupling nutrient signaling to mTOR and also plays a role in autophagy and intracellular trafficking. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.
Spezifikation
Spezifikation
| Zugriffsnummer | Q8NEB9 |
| Konzentration | See Label |
| Zur Verwendung mit (Anwendung) | Kinase Assay |
| Zusammensetzung | 50mM tris with 0.5mM EDTA, 150mM NaCl, 50% glycerol, 2mM DTT, 0.02% CHAPS and no preservative; pH 7.5 |
| Gen-ID (Entrez) | 5289 |
| Molekulargewicht | 129 kDa |
| Name | Human PIK3C3 (hVPS34), GST Tag |
| pH-Bereich | 7.5 |
| Reinigungsverfahren | Purified |
| Menge | 100 μg |
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