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Phospho-BRD4 (Ser1070) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marke: Thermo Scientific PA5117262
Additional Details : Gewicht : 0.01000kg
Beschreibung
Positive Samples: HeLa Immunogen sequence: IHSPQ
BRD4, a ubiquitously expressed nuclear phosphoprotein, is a member of BET protein family. It is a human homolog of mouse MCAP and consists of 2 N-terminal bromodomains, a central ET-domain, and several kinase-like motifs in its N-terminus. It is expressed as 2 isoforms; the longer variant has a C-terminus region with a praline and glutamine-rich domains. BRD4 is a chromatin-binding protein whose expression is induced in response to growth stimuli. BRD4 acts at different stages of the cell cycle by interacting with proteins including RFC and SPA-1 and regulates cell growth. It also has a role in regulating chromosomal dynamics during mitosis. BRD4 functions as a cellular target for E2 protein of papillomavirus.Spezifikation
| Phospho-BRD4 (Ser1070) | |
| Polyclonal | |
| Unconjugated | |
| BRD4 | |
| Brd4; BRD4-NUT FUSION; Brd5; bromodomain containing 4; bromodomain-containing 4; bromodomain-containing 5; bromodomain-containing protein 4; bromodomain-containing protein 4; LOW QUALITY PROTEIN: bromodomain-containing protein 4; CAP; chromosome-associated protein; fsh-like protein; HUNK1; HUNKI; Mcap; mitotic chromosome-associated protein; Protein HUNK1; WI-11513 | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 23476 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 1.4 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| O60885 | |
| BRD4 | |
| A synthetic phosphorylated peptide around S1070 of human BRD4 (NP_4905971) | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |