Gibco™ PeproGMP™ Human IL-6 Recombinant Protein, PeproTech®

Recombinant Protein

The IL-6 protein is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. The PeproTech Recombinant Human IL-6 is a 20.9 kDa protein containing 184 amino acid residues. PeproGMP IL-6 cytokine is most often used with PeproGMP SCF, PeproGMP TPO (thrombopoietin) and PeproGMP Flt3-ligand in hematopoietic stem cells (HSCs) cultures. IL-3 may also be used for further synergistic expansion and immune cell maturation. PeproGMP Recombinant Human IL-6 is also commonly used with PeproGMP IL-2 and PeproGMP IL-15 for B cell cultures. Reconstitute using sterile water (i.e., WFI) to a concentration of 0.1-1.0 mg/ml. Additional product information, specifications, handling and reconstitution information are provided on the Certificate of Analysis. All PeproGMP™ products are manufactured using animal-derived component free materials. Product Description/Intended Use: PeproTech GMP recombinant proteins are manufactured for use as ancillary materials by applying applicable principles of GMP and quality control requirements from USP (United States Pharmacopeia) Chapter <1043> Ancillary Materials for Cell, Gene, and Tissue-Engineered Products.