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PD-L2/CD273 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marke: Proteintech 18251-1-AP-20UL
Additional Details : Gewicht : 0.00010kg
Beschreibung
Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.Spezifikation
PD-L2/CD273 | |
Polyclonal | |
Unconjugated | |
PDCD1LG2 | |
B7 DC, Btdc, Butyrophilin B7 DC, CD273, PD 1 ligand 2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, PDL2, PD-L2, Programmed death ligand 2 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
309304, 58205, 80380 | |
-20°C | |
Liquid |
Western Blot, Immunohistochemistry (Paraffin) | |
0.19 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
Q9BQ51, Q9WUL5 | |
Pdcd1lg2 | |
PD-L2/CD273 Fusion Protein Ag13039 | |
20 μL | |
Primary | |
Mouse, Rat, Human | |
Antibody | |
IgG |